Acetyl Hexapeptide-3 200mg (Topical)


Availability: In stockManufactured in USA

Purity: 99%

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Discover the power of Acetyl Hexapeptide-3 (Topical) for youthful skin. Reduce wrinkles and achieve a smoother complexion with this innovative peptide.

Acetyl Hexapeptide-3 (Topical), also known as Argireline, is a synthetic peptide used in skincare products for its potential anti-aging effects. It has gained popularity in the cosmetic industry due to its ability to reduce the appearance of wrinkles and fine lines.

By inhibiting neurotransmitter release involved in muscle contraction, Acetyl Hexapeptide-3 may help relax facial muscles and smooth out wrinkles caused by repetitive facial expressions. Research studies have suggested that it can temporarily smooth the skin, improve texture, and enhance elasticity. Overall, Acetyl Hexapeptide-3 offers potential benefits for those seeking youthful-looking skin.

Acetyl Hexapeptide-3 200mg (Topical) for Sale
Acetyl Hexapeptide-3 200mg (Topical)
$220.00 Buy Now

Availability: In stockManufactured in USA

Purity: 99%

FREE Shipping for orders over $200 (USA Only)

$15.00 Flat Rate Shipping Worldwide (Most Countries)

*Includes one 30mL Bacteriostatic Water with orders over $300.00


Last updated on November 5, 2023

Revolutionary Anti-Aging Breakthrough: Acetyl Hexapeptide-3 (Topical) Unveils Dramatic Results in Reversing Wrinkles and Fine Lines

Introducing Acetyl Hexapeptide-3 (Topical): A Breakthrough in Skincare!

Studies have shown that Acetyl Hexapeptide-3, a remarkable ingredient in skincare products, offers incredible benefits for your skin. This innovative peptide has been extensively researched and proven to reduce the appearance of fine lines and wrinkles, giving you a more youthful and radiant complexion. With its topical application, this revolutionary product is set to revolutionize your skincare routine. Say hello to smoother, firmer skin with Acetyl Hexapeptide-3!

1. What is Acetyl Hexapeptide-3 (Topical)?

Acetyl Hexapeptide-3 (Topical), also known as Argireline, is a synthetic peptide that is commonly used in skincare products for its potential anti-aging effects. It is a hexapeptide composed of six amino acids: acetyl-glutamyl-glutamyl-methionyl-glutaminyl-arginine. Acetyl Hexapeptide-3 is derived from botulinum toxin, but it does not have the same paralyzing effect on muscles.

This topical peptide has gained popularity in the cosmetic industry due to its ability to reduce the appearance of wrinkles and fine lines. It works by inhibiting the release of neurotransmitters called catecholamines, which are involved in muscle contraction. By reducing muscle activity, Acetyl Hexapeptide-3 may help relax facial muscles and smooth out wrinkles caused by repetitive facial expressions.

2. How Does Acetyl Hexapeptide-3 (Topical) Work?

The mechanism of action of Acetyl Hexapeptide-3 involves its ability to interfere with the formation and release of neurotransmitters involved in muscle contraction. Specifically, it targets the SNARE complex, which plays a crucial role in vesicle fusion and neurotransmitter release at the neuromuscular junction.

Acetyl Hexapeptide-3 competes with the SNAP-25 protein for binding to the vesicle-associated membrane protein (VAMP), preventing proper assembly of the SNARE complex. This disruption inhibits exocytosis and reduces the release of neurotransmitters like acetylcholine, ultimately leading to decreased muscle contractions.

3. Acetyl Hexapeptide-3 (Topical) Benefits

Research studies on Acetyl Hexapeptide-3 have suggested several potential benefits:

  • Reduction of wrinkle depth and fine lines: Acetyl Hexapeptide-3 has been shown to have a temporary smoothing effect on the skin, which may help reduce the appearance of wrinkles and fine lines.
  • Improved skin texture and elasticity: Some studies suggest that Acetyl Hexapeptide-3 may enhance collagen production and improve skin elasticity, leading to a more youthful appearance.
  • Potential anti-inflammatory properties: Preliminary research indicates that Acetyl Hexapeptide-3 may possess anti-inflammatory properties, which could help soothe irritated or inflamed skin.

4. Acetyl Hexapeptide-3 (Topical) Side Effects

In non-human research studies, Acetyl Hexapeptide-3 has generally been well-tolerated with no reported significant side effects. However, individual reactions can vary, and it is always recommended to perform a patch test before applying any new skincare product containing this peptide. Some individuals may experience mild irritation or allergic reactions to the compound.

It is important to note that while Acetyl Hexapeptide-3 is considered safe for topical use in skincare products, its safety profile for other routes of administration or long-term use has not been extensively studied. As with any cosmetic ingredient, it is advisable to consult with a healthcare professional or dermatologist before incorporating Acetyl Hexapeptide-3 into your skincare routine.

5. Advantages of Acetyl Hexapeptide-3 (Topical)

Acetyl Hexapeptide-3 offers several advantages compared to other anti-wrinkle treatments:

  • Non-invasive: Unlike injectable treatments like Botox, Acetyl Hexapeptide-3 is applied topically and does not require injections or invasive procedures.
  • No downtime: Topical application of Acetyl Hexapeptide-3 allows for convenient use without any recovery period or downtime.
  • Targeted application: The topical formulation allows precise targeting of specific areas of concern, such as crow’s feet or forehead wrinkles.
  • Cost-effective: Compared to more invasive cosmetic procedures, Acetyl Hexapeptide-3 can be a more affordable option for individuals seeking temporary wrinkle reduction.

6. Acetyl Hexapeptide-3 (Topical) Research Topics

The current research on Acetyl Hexapeptide-3 focuses on various topics:

  • Efficacy in reducing different types of wrinkles and fine lines
  • Potential long-term effects and safety considerations
  • Synergistic effects with other skincare ingredients or treatments
  • Optimal formulation and delivery methods for enhanced penetration and efficacy

7. Future Research Directions for Acetyl Hexapeptide-3 (Topical)

While Acetyl Hexapeptide-3 has shown promise in non-human research studies, there are still several areas that require further investigation:

  • Long-term safety profile: More extensive studies are needed to assess the long-term safety of Acetyl Hexapeptide-3 when used in skincare products.
  • Efficacy comparison with other anti-wrinkle treatments: Comparative studies can help determine the effectiveness of Acetyl Hexapeptide-3 in relation to other established anti-wrinkle treatments.
  • Optimization of formulation and delivery methods: Research efforts can focus on developing innovative formulations and delivery systems to enhance the stability, penetration, and efficacy of Acetyl Hexapeptide-3.

8. Acetyl Hexapeptide-3 (Topical) Before and After in Research

In non-human research studies, Acetyl Hexapeptide-3 has demonstrated visible improvements in the appearance of wrinkles and fine lines. Before treatment, subjects may exhibit signs of aging such as deep wrinkles, crow’s feet, or forehead lines. However, after using topical formulations containing Acetyl Hexapeptide-3 for a specified period, researchers have observed:

  • Reduction in wrinkle depth and length
  • Smoothing out of fine lines
  • Improved overall skin texture and tone

9. Acetyl Hexapeptide-3 (Topical) Cycle for Research

The recommended cycle for research purposes may vary depending on the specific study design and objectives. However, typical protocols for evaluating the effects of Acetyl Hexapeptide-3 may involve:

  • Baseline assessment: Establishing the initial condition of the skin by measuring wrinkle depth, skin elasticity, or other relevant parameters.
  • Treatment phase: Applying a topical formulation containing Acetyl Hexapeptide-3 according to the recommended dosage and frequency.
  • Follow-up assessments: Periodically evaluate the changes in wrinkle depth, skin texture, or other desired outcomes at predetermined intervals during or after the treatment phase.

10. Best Acetyl Hexapeptide-3 (Topical) Results in Research

Based on non-human research studies, some of the most promising results achieved with Acetyl Hexapeptide-3 include:

  • Significant reduction in wrinkle depth and length, particularly in areas prone to dynamic wrinkles caused by repetitive facial movements.
  • Improvement in overall skin texture and elasticity leads to a smoother and more youthful appearance.
  • Potential synergistic effects when combined with other skincare ingredients or treatments, enhancing the overall anti-aging benefits.

11. Where to Buy Acetyl Hexapeptide-3 (Topical)?

To purchase Acetyl Hexapeptide-3 (Topical), you can visit the website of ResearchPeptides is a reputable supplier of high-quality peptides for research purposes. They offer Acetyl Hexapeptide-3 in various formulations and quantities, ensuring flexibility and convenience for researchers.

12. Acetyl Hexapeptide-3 (Topical) for Sale

If you are interested in exploring the potential benefits of Acetyl Hexapeptide-3 (Topical), it is available for sale through Research Peptides. As a trusted source of research peptides, ResearchPeptides ensures the quality and purity of its products to support accurate and reliable scientific investigations.

Dosage, Mixing, and Storage:

The recommended dosage of Acetyl Hexapeptide-3 for non-human research purposes may vary depending on the specific study design and objectives. It is essential to refer to relevant scientific literature or consult with a knowledgeable professional for appropriate dosage guidance.

When preparing Acetyl Hexapeptide-3 for use in experiments, it is crucial to follow proper mixing instructions provided by the supplier. The compound may come in a lyophilized form that needs reconstitution with a suitable solvent or buffer. Care should be taken to ensure accurate measurement and proper dissolution.

To maintain the stability and effectiveness of Acetyl Hexapeptide-3, it is recommended to store the peptide in a cool, dry place away from direct sunlight. Following the storage guidelines provided by the supplier can help preserve the integrity of the compound for extended periods.

In light of the extensive research conducted on Acetyl Hexapeptide-3 (Topical), it is evident that this product holds remarkable potential in the field of skincare. The studies consistently demonstrate its effectiveness in reducing the appearance of wrinkles and fine lines, making it a promising solution for individuals seeking youthful and radiant skin. With its proven benefits, Acetyl Hexapeptide-3 (Topical) offers an exciting avenue for improving skin health and enhancing overall confidence.

Frequently Asked Questions About Acetyl Hexapeptide-3 (Topical) Peptides February 2024

What Cannot be used with Argireline?

It is not recommended to use Argireline™ with direct acids like L-ascorbic acid (LAA) or ethylated ascorbic acid (EAA) because direct acids can cause skin irritation. Combining them with Argireline™ may further increase the risk of irritation. Therefore, Vitamin C & Argireline™ should not be used together with direct acids.

Does Argireline cause skin sagging?

There is no scientific evidence to suggest that Argireline causes skin sagging.

What are the risks of Argireline?

As Argireline is a new product in the market, there is limited information available regarding its potential side effects. It is advisable to carefully examine the ingredient list of the product you are using, as your skin may react to a different ingredient even if you are not allergic to Argireline itself.

What is better than Argireline?

Both Snap-8 and Argireline can be used twice a day, but Snap-8 has been shown to be 30% more effective than Argireline. Snap-8 also has better results in reducing the depth of wrinkles. Argireline is an excellent alternative to botulinum toxin and works by releasing neurotransmitters at the terminal end of snap-25 through the use of the SNARE complex.

Is Argireline like Botox?

Argireline is a peptide that functions by blocking the release of neurotransmitters in the neuromuscular junction, resulting in a similar effect to Botox.

Is Argireline safe to use under eyes?

According to Shah, Argireline helps increase the production of collagen and enhances its function, leading to the reduction of fine lines and improved skin hydration. It is recommended for individuals who want to minimize wrinkles caused by repetitive muscle movements, particularly on the forehead and around the eyes.

Peptides Explored: Your Comprehensive Resource 2024

The Peptides Store offers a wide array of peptide forms, such as protein chains, peptide mixtures, IGF-1 Proteins, Melanotan proteins, and beauty peptides. Our Research Peptides platform provides extensive resources for those interested in the science of peptides. We also offer a variety of Lab Supplies for your research needs. Our Peptides Knowledge Base is a great resource for expanding your understanding of peptides.

Author Info and References

Author Info

The information provided in this article was taken from studies carried out by recognized researchers, including K. Tadini, D. G. Mercurio, P. M. Campos, N. V. Sautina, Enzhe M. Miftahova, Kseniya V. Silakhina, Y. Galyametdinov, Moongi Ji, Hyeon‐Seong Lee, Youngbae Kim, Chan Seo, Subin Choi, Songjin Oh, Jeuk Min, Hyung‐Jin Park, Jung Dong Kim, Do Hyeon Jeong, M. Paik, A. Dragomirescu, M. Andoni, D. Ionescu, and F. Andrei.


  1. Tadini, K., Mercurio, D. G., & Campos, P. M. (2015). Acetyl hexapeptide-3 in a cosmetic formulation acts on skin mechanical properties – clinical study. Brazilian Journal of Pharmaceutical Sciences.
  2. Sautina, N. V., Miftahova, E. M., Silakhina, K. V., & Galyametdinov, Y. (2019). RELEASING OF ACETYL HEXAPEPTIDE-3 USING A LECITHIN BASED LIQUID CRYSTAL SYSTEM. Chemistry and Technology.
  3. Ji, M., Lee, H., Kim, Y., Seo, C., Choi, S., Oh, S., Min, J., Park, H., Kim, J. D., Jeong, D. H., & Paik, M. (2020). Method development for acetyl octapeptide-3 analysis by liquid chromatography-tandem mass spectrometry. Journal of Analytical Science and Technology.
  4. Dragomirescu, A., Andoni, M., Ionescu, D., & Andrei, F. (2014). The Efficiency and Safety of Leuphasyl—A Botox-Like Peptide. Cosmetics.

Acetyl Hexapeptide 3 Research Peptides Scientists

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Cite this article as: Research Peptides Scientist, "Acetyl Hexapeptide-3 200mg (Topical)," in, November 5, 2023, Accessed February 1, 2024.


Product Usage: THIS PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. This product has not been approved by the FDA for Human Use. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.


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