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Rigin 200mg (Palmitoyl Tetrapeptide-7)
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Rigin Peptide, the Promising Antiaging Formula
Rigin, otherwise known as Palmitoyl Tetrapeptide-7, is a synthetic peptide made up of four amino acids, used in beauty products. It works by suppressing excess interleukins production, which initiates the body’s acute inflammatory response, leading to glycation damage. Glycation damage significantly affects the skin’s support system, compromising collagen levels and production, which results in fine lines, wrinkles, and sagging skin.
Researchers are interested in learning more about rigin peptide and its effects on the skin. Further investigations suggest Palmitoyl Tetrapeptide 7 can also improve skin hydration by controlling the secretion of cytokines.
In this article, we’re going to delve deeper into what this peptide is, its functions, and where to buy rigin peptide.
What is Palmitoyl Tetrapeptide 7?
Rigin[i] is a fragment of the IgG antibody found in many mammals. It was first developed after another tetrapeptide, tuftsin, displayed potent neurotrophic and immunostimulatory activities. Rigin is a promising peptide in the world of beauty and cosmetics.
According to research, Palmitoyl Tetrapeptide can stimulate the regeneration of collagen fibers in the dermis by serving as a cellular messenger. What’s more, it can heighten hyaluronic acid levels in the skin, promoting firmer, tighter, smoother skin.
It’s just one of many peptides recently discovered for its plethora of skin benefits. However, rigin peptide is one of the most common found in antiaging creams, serums, and moisturizers.
A study reviewed by the Cosmetic Ingredient Review Expert Panel showed a significant increase in skin elasticity, improved skin texture, and a reduction in deep wrinkles. The study also found that this peptide delivered a dose-response for collagen 1, hyaluronic acid, and fibronectin synthesis.
How Does Rigin Work?
Research shows that rigin can modulate the production of interleukin-6, a signalling molecule that recruits additional immune cells to the site of infection or damage.
In some cases, the immune response may become too large, resulting in damaged healthy tissue and damaged ECM, reducing elastin and collagen. Palmitoyl Tetrapeptide-7 can counteract the effects of IL-6 by lessening the impact of the immune response and shielding the skin from harm.
In animal models, rigin exhibits activity against matrix metalloproteinases (MMPs) – a group of enzymes that play a role in the breakdown of ECM proteins during healthy tissue growth.
Rigin can downregulate the activity of MMPs, reducing ECM damage and enabling cells to promote restoration and maintenance of the ECM. Many researchers compare rigin to dehydroepiandrosterone, which is often known as the youth hormone.
Benefits of Palmitoyl Tetrapeptide 7
Palmitoyl Tetrapeptide-7 peptide is primarily used in antiaging products thanks to its ability to reduce wrinkles and improve skin elasticity. New research shows that rigin could also help reduce cell damage during inflammation, uneven skin tone, and pigmentation. Other studies show it can treat rosacea too.
While the research looks promising, you should understand that more studies need to be carried out in order for it to be recognized as an antiaging skincare elixir.
Currently, there is not enough research to make these claims.
Rigin Skincare Effects
Animal research and studies on human skin cells[ii] show how rigin can improve the appearance of wrinkles and reduce the effects of aging skin.
It demonstrates how effective Palmitoyl Tetrapeptide-7 is on reducing the appearance of fine lines and wrinkles, as well as evening out the skin tone and enhancing skin hydration.
Rigin can also be combined with other ingredients such as palmitoyl oligopeptide to boost skin rejuvenation.
It’s incredibly interesting to see just how powerful this peptide is at replenishing and rejuvenating the skin. Even though research might be young, it’s clear that this peptide offers several benefits regarding skin. That’s why it’s hardly surprising that so many scientists are keen to get their hands on this peptide for their own research studies. With more sufficient evidence of its skincare benefits, rigin peptide should be available in a range of antiaging products. It could even make its way into supplements and replace collagen as the number 1 antiaging ingredient.
Palmitoyl Tetrapeptide Safety
The Cosmetic Ingredient Review Expert Panel reviewed the data on rigin peptide to determine it is safe for use.
At present, there are no reported issues regarding toxicity, hormone disruption or sensitivity. Still, rigin is quite a new ingredient and further information will be required to make future reviews on this product.
According to the panel, there are certain reported side effects relating to pigmentation. That’s because rigin can break down skin pigmentation, which can often lead to skin discoloration issues.
Overall, the peptide Palmitoyl Tetrapeptide-7 is an effective ingredient with a host of skincare benefits. It is considered safe by experts, but will require further testing to make it FDA-approved.
Rigin Review 2021
Rigin was first developed as a potential neurotrophic and potential immunostimulatory. It is still under investigation for its use in promoting nerve healing, even skin tone, and youthful skin.
Researchers are currently interested in learning more about how extracellular matrix growth is modulated and rigin’s involvement. We already know that rigin can influence collagen and elastin synthesis in the ECM, but scientists suspect it may offer several other benefits as well.
Palmitoyl Tetrapeptide-7 is a type of synthetic peptide compound comprised of amino acids that work to reduce skin inflammation and damage. Experts say this peptide compound can also stimulate the regeneration of collagen fibers in the dermis. In the coming years, we suspect it will be a popular antiaging ingredient and that we’ll uncover more benefits of rigin peptide.
Buy Rigin Peptide
You will find rigin for sale at a range of online suppliers. However, we do urge you to carry out adequate research prior to purchasing this product online.
You can buy Palmitoyl Tetrapeptide-7 directly from Peptide Sciences – our favorite online vendor for high-quality peptides in the United States. Their products are all manufactured in the USA and abide by strict health and safety regulations to ensure only the best, safest, and most efficient product.
Order Rigin 200mg, click here to buy today.
Author info: The information provided in this article was taken from studies carried out by recognized researchers including Ahsan, Haseeb, Mondon, Philippe, Mélanie Hillion, Olivier Peschard, Nada Andre, Thibault Marchand, Emmanuel Doridot, Marc GJ Feuilloley, Cédric Pionneau, and Solenne Chardonnet.
[i] Ahsan, Haseeb. “Immunopharmacology and Immunopathology of Peptides and Proteins in Personal Products.” Journal of Immunoassay and Immunochemistry 40, no. 4 (June 17, 2019): 439–447. doi:10.1080/15321819.2019.1629590.
[ii] Mondon, Philippe, Mélanie Hillion, Olivier Peschard, Nada Andre, Thibault Marchand, Emmanuel Doridot, Marc GJ Feuilloley, Cédric Pionneau, and Solenne Chardonnet. “Evaluation of Dermal Extracellular Matrix and Epidermal-Dermal Junction Modifications Using Matrix-Assisted Laser Desorption/ionization Mass Spectrometric Imaging, in Vivo Reflectance Confocal Microscopy, Echography, and Histology: Effect of Age and Pepti.” Journal of Cosmetic Dermatology 14, no. 2 (March 27, 2015): 152–160. doi:10.1111/jocd.12135.
Rigin Research Peptides Scientists
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December 31, 2020 12:00 AM