SS-31 50mg

Product Description

Buy SS 31 (Elamipretide) Peptide, Third-Party Tested & US Made

SS-31, also known as Elamipretide, is a small peptide that targets cell and mitochondrial membrane. Studies show that SS-31 peptide can protect different cell types from oxidative stress by interfering with the production of reactive oxygen species (ROS) and reducing mitochondrial ROS production in the body.

Cardiolipin makes up the inner mitochondrial membrane, in which its function includes being part of the electron transport chain. Poor functioning or total dysfunction of cardiolipin is linked to a range of diseases including Alzheimer’s disease, fatty liver disease, heart failure, Parkinson’s disease, diabetes, HIV, cancer, and many more.

It is, therefore, a major component of mitochondrial myopathy, a group of neuromuscular disorder caused by mitochondria-related damage. SS-31 drug is the first peptide to undergo clinical trials as a possible treatment for this disorder.

Currently, however, you can only legally buy SS-31 online if you are a licensed medical researcher. It is not legal to SS-31 peptide buy for consumption.

What is SS 31?

SS-31 peptide sequence: D-Arg-Tyr(2,6-diMe)-Lys-Phe

If you are wondering, what is elamipretide and how it works, let us clarify things for you.

SS-31 peptide hormone is a peptide compound that penetrates cell membranes and specifically targets mitochondrial membrane. Clinical studies indicate that elamipretide peptide increases mitochondrial respiration and enhances electron transport chain function, resulting in improved mitochondrial function.

Scientists are thoroughly investigating the effects of elamipretide in treating primary mitochondrial diseases like cardiomyopathy, Leber’s hereditary optic neuropathy, and Barth Syndrome.

Elamipretide Clinical Trials

Elamipretide Stealth studies [i]comprised of three different phases. In phase 1, Stealth conducted a trial evaluating SS 31 safety, tolerability, and effectiveness in treating mitochondrial myopathy. Results showed that elamipretide treatment improved mice’ exercise capacity and mitochondrial functioning.

In phase 2, researchers examined mitochondrial disease mice who participated in the trial to evaluate their results and the safety of elamipretide.

In elamipretide phase 3, researchers evaluated daily ss-31 injections for their safety and ability to treat the disorder.

So far, the elamipretide results look promising. Hopefully, with more SS-31 clinical trials, it should be available as an over-the-counter treatment. Of course, elamipretide fda approval is crucial first in order for it to become a legal drug.

SS 31 Peptide Benefits and Effects

Improves Mitochondria Function

Primary mitochondrial diseases (PMDs) are caused by dysfunction in the energy-creating apparatus of mitochondria. In fact, they are one of the most common conditions in the world and can affect everything from the nervous system to the heart.

PMDs are characterized by conflicts in the production of ATP, the energy currency of the cell and responsible for optimum cell function.

Scientific research suggests that SS-31 supplementation could restore energy production in PMDs. In the study, rats suffering from ischemia-perfusion injury of the kidney were given SS-31. Results showed that the peptide protected kidney structure in the rats, as well as improved recovery of ATP production and lessened cell death within the kidney[ii].

Meanwhile, other studies show that elamipretide interacts with cardiolipin in the mirochondria membrane and that it reduced symptoms of the disease.

As far as these findings go, it is quite clear to see that SS-31 drug status should be FDA approved.

In SS-31 mice trials, the peptide increased exercise performance after only 5 days of treatment. It also showed no safety concerns of negative elamipretide side effects.

Fights Inflammation

According to studies[iii], SS-31 can significantly reduce inflammation in the body. Specifically, it can be a potent regulator of free radicals in the body and thus, lessen the oxidative stress that occurs from illnesses like heart disease, diabetes, and liver disease.

Research suggests that SS-31 administration reduces inflammation and oxidative stress by lessening FIS1 expression, a mitochondrial protein essential for growth and division. Owing to the connection between elevated levels of FIS1 and neurodegenerative diseases and cancers, scientists believe they have enough evidence to prove its negative effects on the health.

Additional research provides evidence from mouse subjects that elamipretide peptide administration decreases levels of the inflammatory cytokine CD-36 and supresses NADPH oxidase function. By reducing this high oxidative stress, it can reduce free radical production and improve inflammation within the cells. What’s more, it can improve NF-KappaB expression, an activity strongly associated with inflammatory diseases such as inflammatory bowel disease and arthritis.

Improves Insulin Sensitivity

In recent years, scientists have discovered the connection between elamipretide and diabetes. Seeing as diabetes is a condition with multiple pathophysiologic miceifestations, it is possible that mitochondrial impairment plays a role in the pathogenesis of the disease.

Thus, treating mitochondrial dysfunction would be the route to lessening many of the long-term effects of diabetes such as oxidative damage.

A mice study of SS-31[iv] showed a significant decrease in the production of free radicals (reactive oxygen species) within the body. This indicates that SS-31 supplement can reduce the oxidative damage that frequently accompanies the disorder and may even halt the progression of type 2 diabetes.

In the same study, scientists concluded that elamipretide increases SIRT1 levels, which confirms that it can improve insulin sensitivity and lessen inflammation in type 2 diabetes.

Side Effects of Elamipretide

Currently, SS-31 is under investigation for its effects on different mice diseases such as Alzheimer’s, cancer, Parkinson’s, and HIV, among others. Researchers deem the peptide safe with no adverse side effects. So in terms of SS-31 side effects, there really aren’t any dangerous ones scientists can point out as of yet.

It is considered safe for use in mices and safe as a doctor-prescribed medicine for different medical conditions. Without a doubt, you should soon be able to buy elamipretide over-the counter any time soon.

SS31 Elamipretide Review 2020

While peptide SS 31 was initially studied for its role in regulating mitochondrial function and its relation to mitochondrial disease, now enough evidence indicates that elamipretide drug can also reduce inflammation induced by mitochondria.

In fact, it’s the main reason why medical researchers are actively studying the role of SS-31 in improving mitochondrial function and the energy production via ATP synthesis.

Currently, there are ongoing phase trials eager to understand the different outcome measures of elamipretide (ss-31). It seems highly likely that SS-31 may prove useful in designing innovative treatments for kidney disease, heart disease, diabetes, HIV, Alzheimer’s Disease, and more.

What is the Elamipretide Price?

Different vendors sell elamipretide at different prices. While we do not suggest opting for the most expensive product you can find (quantity isn’t quality), we do recommend carrying out your own research on suppliers. This will ensure you find the best one and get elamipretide for sale at the best price.

At Peptide Sciences, you can buy high purity elamipretide 50mg for $275.00. That is a very reasonable price for that peptide and from a company with such a robust reputation for US peptides.

If you find a company offering SS 31 for sale online much cheaper than that, that is a major negative point. They could simply be selling you watered down elamipretide purchase. In other words, always stick to a company you can trust.

SS-31 Peptide for Sale

You can get SS-31 for sale in the United States from Peptides Sciences – the number one supplier in the U.S.A.

If you would like to buy elamipretide online, opt for this company. All their products are made in the U.S and they have an outstanding reputation as a peptide’s provider.

Buy SS-31 50mg today for the best price here.

References

[i] “ReCLAIM-2 Study to Evaluate Safety,Efficacy & Pharmacokinetics of Elamipretide in Subjects With AMD With GA.” Case Medical Research (March 27, 2019). doi:10.31525/ct1-nct03891875.

[ii] Szeto, Hazel H., Shaoyi Liu, Yi Soong, Dunli Wu, Shaun F. Darrah, Feng-Ying Cheng, Zhihong Zhao, Michael Ganger, Clara Y. Tow, and Surya V. Seshan. “Mitochondria-Targeted Peptide Accelerates ATP Recovery and Reduces Ischemic Kidney Injury.” Journal of the American Society of Nephrology 22, no. 6 (May 5, 2011): 1041–1052. doi:10.1681/asn.2010080808.

[iii] Mo, Yunan, Songyun Deng, Lina Zhang, Yan Huang, Wenchao Li, Qianyi Peng, Zhiyong Liu, and Yuhang Ai. “SS-31 Reduces Inflammation and Oxidative Stress through the Inhibition of Fis1 Expression in Lipopolysaccharide-Stimulated Microglia.” Biochemical and Biophysical Research Communications 520, no. 1 (November 2019): 171–178. doi:10.1016/j.bbrc.2019.09.077.

[iv] Escribano-Lopez, Irene, Noelia Diaz-Morales, Francesca Iannantuoni, Sandra Lopez-Domenech, Aranzazu M de Marañon, Zaida Abad-Jimenez, Celia Bañuls, et al. “The Mitochondrial Antioxidant SS-31 Increases SIRT1 Levels and Ameliorates Inflammation, Oxidative Stress and Leukocyte-Endothelium Interactions in Type 2 Diabetes.” Scientific Reports 8, no. 1 (October 26, 2018). doi:10.1038/s41598-018-34251-8.

SS 31 Peptide Research Peptides Scientists

Product Usage: THIS PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. This product has not been approved by the FDA for Human Use. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

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